Gelsolin antibody

Catalog No. ABIN8121626

This Rabbit Polyclonal antibody specifically detects Gelsolin in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Gelsolin antibody (ABIN8121626)

Target: Gelsolin (GSN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gelsolin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Gelsolin Antibody

Purpose: GELS Antibody

Specificity: GELS Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Gelsolin

Target: Gelsolin (GSN)

Alternative Name: GELS

Background:

Background: The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: GSN

Protein Name: Gelsolin (AGEL) (Actin-depolymerizing factor) (ADF) (Brevin)

Gene ID: 2934

UniProt: P06396

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, Autophagy