GTF3A antibody

Catalog No. ABIN8121637

The Rabbit Polyclonal anti-GTF3A antibody (ABIN8121637) specifically detects GTF3A in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GTF3A antibody (ABIN8121637)

Target: GTF3A (General Transcription Factor IIIA (GTF3A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GTF3A Antibody

Purpose: TFIIIA Antibody

Specificity: TFIIIA Polyclonal Antibody detects endogenous levels of TFIIIA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TFIIIA.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GTF3A

Target: GTF3A (General Transcription Factor IIIA (GTF3A))

Alternative Name: TFIIIA

Background:

Synonyms: GTF3A, Transcription factor IIIA, TFIIIA

Background: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008],

Gene Name: GTF3A

Protein Name: Transcription factor IIIA

Gene ID: 2971

UniProt: Q92664