GPT2 antibody (AA 190-270)

Catalog No. ABIN8121694

The Rabbit Polyclonal anti-GPT2 antibody (ABIN8121694) specifically detects GPT2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GPT2 antibody (AA 190-270) (ABIN8121694)

Target: GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GPT2 Antibody

Binding Specificity: AA 190-270

Purpose: GPT2 Antibody

Specificity: GPT2 Polyclonal Antibody detects endogenous levels of GPT2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from GPT2 . at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GPT2

Target: GPT2 (Glutamic Pyruvate Transaminase (Alanine Aminotransferase) 2 (GPT2))

Alternative Name: GPT2

Background:

Synonyms: GPT2, AAT2, ALT2, Alanine aminotransferase 2, ALT2, Glutamate pyruvate transaminase 2, GPT 2, Glutamic--alanine transaminase 2, Glutamic--pyruvic transaminase 2

Background: This gene encodes a mitochondrial alanine transaminase, a pyridoxal enzyme that catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Alanine transaminases play roles in gluconeogenesis and amino acid metabolism in many tissues including skeletal muscle, kidney, and liver. Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of function mutation in this gene has been associated with developmental encephalopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Gene Name: GPT2

Protein Name: Alanine aminotransferase 2

Gene ID: 84706

UniProt: Q8TD30