Glutaredoxin 1 antibody (AA 40-120)

Catalog No. ABIN8121704

This Rabbit Polyclonal antibody specifically detects Glutaredoxin 1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Glutaredoxin 1 antibody (AA 40-120) (ABIN8121704)

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Glutaredoxin 1 Antibody

Binding Specificity: AA 40-120

Purpose: GLRX1 Antibody

Specificity: GLRX1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX1

Background:

Background: This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011],

Gene Name: GLRX GRX

Protein Name: Glutaredoxin-1 (Thioltransferase-1) (TTase-1)

Gene ID: 2745

UniProt: P35754

Pathways: Cell RedoxHomeostasis