GSTM3 antibody (AA 1-51)

Catalog No. ABIN8121721

The Rabbit Polyclonal anti-GSTM3 antibody (ABIN8121721) specifically detects GSTM3 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GSTM3 antibody (AA 1-51) (ABIN8121721)

Target: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTM3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSTM3 Antibody

Binding Specificity: AA 1-51

Purpose: GSTM3 Antibody

Specificity: This antibody detects endogenous levels of GSTM3 at Human

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GSTM3 AA range: 1-51

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GSTM3

Target: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Alternative Name: GSTM3

Background:

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008],

Gene Name: GSTM3 GST5

Protein Name: GSTM3

Gene ID: 2947

UniProt: P21266