GSTP1 antibody (AA 150-210)

Catalog No. ABIN8121729

The Mouse Monoclonal anti-GSTP1 antibody is suitable to detect GSTP1 in samples from Human. It has been validated for IHC.

Quick Overview for GSTP1 antibody (AA 150-210) (ABIN8121729)

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GSTP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1548

Product Details anti-GSTP1 Antibody

Binding Specificity: AA 150-210

Purpose: GST-Pi mouse mAb

Specificity: The antibody can specifically recognize human GST-Pi protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 210 of the human GST - Pi protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for GSTP1

Target: GSTP1 (Glutathione S-Transferase pi 1 (GSTP1))

Alternative Name: GST-Pi

Background:

Synonyms: GSTP1 FAEES3 GST3

Background: GST-Pi is a major isoenzyme in GST family. It widely exists in the cytoplasm and mitochondria of human organs and has detoxification function. At present, it is considered to be a marker of drug resistance in tumor cells. GST-Pi is highly expressed in a variety of tumors, which is related to tumor treatment drug resistance. The simultaneous detection of GST-Pi with P-gp and TopoII has more clinical significance for judging whether tumor cells produce drug resistance.

Gene Name: Glutathione S-transferase P (EC 2. 5. 1. 18) (GST class-pi) (GSTP1-1)

Protein Name: GST-Pi

Gene ID: 2950

UniProt: P09211

Pathways: Cellular Response to Molecule of Bacterial Origin