GTPBP4 antibody (AA 580-660)

Catalog No. ABIN8121834

The Rabbit Polyclonal anti-GTPBP4 antibody is suitable to detect GTPBP4 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for GTPBP4 antibody (AA 580-660) (ABIN8121834)

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTPBP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GTPBP4 Antibody

Binding Specificity: AA 580-660

Purpose: NOG1 Antibody

Specificity: NOG1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 580-660

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GTPBP4

Target: GTPBP4 (GTP Binding Protein 4 (GTPBP4))

Alternative Name: NOG1

Background:

Background: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008],

Gene Name: GTPBP4 CRFG NOG1

Protein Name: Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB)

Gene ID: 23560

UniProt: Q9BZE4