HSPB8 antibody

Catalog No. ABIN8121889

The Rabbit Polyclonal anti-HSPB8 antibody (ABIN8121889) specifically detects HSPB8 in WB. The antibody is reactive with Human samples.

Quick Overview for HSPB8 antibody (ABIN8121889)

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPB8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HSPB8 Antibody

Purpose: Crystallin-αC Antibody

Specificity: The antibody detects endogenous Crystallin-αC protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Recombinant Protein of Crystallin-alphaC

Isotype: IgG

Application Details

Application Notes: WB 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Alternative Name: Crystallin-alphaC

Background:

Synonyms: HSPB8, CRYAC, E2IG1, HSP22, PP1629, Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22

Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],

Gene Name: HSPB8

Protein Name: Heat shock protein beta-8

Gene ID: 26353

UniProt: Q9UJY1