Histone H1 antibody

Catalog No. ABIN8121994

The Rabbit Polyclonal anti-Histone H1 antibody (ABIN8121994) specifically detects Histone H1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Histone H1 antibody (ABIN8121994)

Target: Histone H1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H1 Antibody

Purpose: Histone H1 (Di Methyl Lys25) Antibody

Specificity: The antibody detects endogenous Histone H1 (Di Methyl Lys25) protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide of Histone H1 (Di Methyl Lys25)

Isotype: IgG

Application Details

Application Notes: WB 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Histone H1

Target: Histone H1

Background:

Synonyms: H1K25ME2, HIST1H1A, H1F1, Histone H1.1, Histone H1a, HIST1H1C, H1F2, Histone H1.2, Histone H1c, Histone H1d, Histone H1s-1, HIST1H1D, H1F3, Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1E, H1F4, Histone H1.4, Histone H1b, Histone H1s-4

Background: Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],

Gene Name: HIST1H1A/HIST1H1C/HIST1H1D/HIST1H1E

Protein Name: Histone H1.1/Histone H1.2/Histone H1.3/Histone H1.4

Gene ID: 3024, 3006, 3007

UniProt: Q02539