INPP5J antibody (AA 850-930)

Catalog No. ABIN8122204

The Rabbit Polyclonal anti-INPP5J antibody (ABIN8122204) specifically detects INPP5J in IHC, ELISA and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for INPP5J antibody (AA 850-930) (ABIN8122204)

Target: INPP5J (Inositol Polyphosphate-5-Phosphatase J (INPP5J))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INPP5J antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-INPP5J Antibody

Binding Specificity: AA 850-930

Purpose: INPP5J Antibody

Specificity: INPP5J Polyclonal Antibody detects endogenous levels of INPP5J protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from INPP5J . at AA range: 850-930

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for INPP5J

Target: INPP5J (Inositol Polyphosphate-5-Phosphatase J (INPP5J))

Alternative Name: INPP5J

Background:

Synonyms: INPP5J, PIB5PA, PIPP, Phosphatidylinositol 4, 5-bisphosphate 5-phosphatase A, Inositol polyphosphate 5-phosphatase J

Background: catalytic activity:1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.,catalytic activity:D-myo-inositol 1,4,5-trisphosphate + H(2)O = myo-inositol 1,4-bisphosphate + phosphate.,domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.,function:Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.,PTM:Phosphorylated at Ser/Thr residues.,similarity:Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.,subcellular location:Predominantly localized to membrane ruffles.,

Gene Name: INPP5J

Protein Name: Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

Gene ID: 27124

UniProt: Q15735