Integrin alpha 1 antibody (AA 920-980)

Catalog No. ABIN8122248

The Rabbit Polyclonal anti-Integrin alpha 1 antibody is suitable to detect Integrin alpha 1 in samples from Human, Mouse and Rat. It has been validated for IHC, ELISA and IF.

Quick Overview for Integrin alpha 1 antibody (AA 920-980) (ABIN8122248)

Target: Integrin alpha 1 (ITGA1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin alpha 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Integrin alpha 1 Antibody

Binding Specificity: AA 920-980

Purpose: Integrin α1 Antibody

Specificity: The antibody detects endogenous Integrin α1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 920-980

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: Integrin alpha1

Background:

Synonyms: Integrin alpha-1 (CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD antigen CD49a)

Background: integrin subunit alpha 1(ITGA1) Homo sapiens This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008],

Gene Name: ITGA1

Protein Name: Integrin alpha-1 (CD49 antigen-like family member A) (Laminin and collagen receptor) (VLA-1) (CD antigen CD49a)

Gene ID: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex