Integrin beta 7 antibody (AA 671-720)

Catalog No. ABIN8122265

This Rabbit Polyclonal antibody specifically detects Integrin beta 7 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Integrin beta 7 antibody (AA 671-720) (ABIN8122265)

Target: Integrin beta 7 (ITGB7)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Integrin beta 7 Antibody

Binding Specificity: AA 671-720

Purpose: Integrin β7 Antibody

Specificity: Integrin β7 Polyclonal Antibody detects endogenous levels of Integrin β7

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Integrin beta7. at AA range: 671-720

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Integrin beta 7

Target: Integrin beta 7 (ITGB7)

Alternative Name: Integrin beta7

Background:

Synonyms: Integrin beta-7 (Gut homing receptor beta subunit)

Background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],

Gene Name: ITGB7

Protein Name: Integrin β7

Gene ID: 3695

UniProt: P26010

Pathways: Integrin Complex