KALRN antibody (AA 810-890)

Catalog No. ABIN8122401

The Rabbit Polyclonal anti-KALRN antibody is suitable to detect KALRN in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for KALRN antibody (AA 810-890) (ABIN8122401)

Target: KALRN (Kalirin, RhoGEF Kinase (KALRN))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KALRN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KALRN Antibody

Binding Specificity: AA 810-890

Purpose: Duo Antibody

Specificity: Duo Polyclonal Antibody detects endogenous levels of Duo protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Duo . at AA range: 810-890

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KALRN

Target: KALRN (Kalirin, RhoGEF Kinase (KALRN))

Alternative Name: Duo

Background:

Synonyms: KALRN; DUET; DUO; HAPIP; TRAD; Kalirin; Huntingtin-associated protein-interacting protein; Protein Duo; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain

Background: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin.This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016],

Gene Name: KALRN

Protein Name: Kalirin

Gene ID: 8997

UniProt: O60229

Pathways: Neurotrophin Signaling Pathway