KPNA6 antibody (AA 404-454)

Catalog No. ABIN8122417

The Rabbit Polyclonal anti-KPNA6 antibody (ABIN8122417) specifically detects KPNA6 in WB and IP. The antibody is reactive with Human and Mouse samples.

Quick Overview for KPNA6 antibody (AA 404-454) (ABIN8122417)

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KPNA6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-KPNA6 Antibody

Binding Specificity: AA 404-454

Purpose: KPNA6 Antibody

Specificity: This antibody detects endogenous levels of KPNA6 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human KPNA6 AA range: 404-454

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KPNA6

Target: KPNA6 (Karyopherin alpha 6 (Importin alpha 7) (KPNA6))

Alternative Name: KPNA6

Background:

Synonyms: Importin subunit alpha-7 (Karyopherin subunit alpha-6)

Background: Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore.The protein encoded byThis gene is a member of the importin alpha family. [provided by RefSeq, Jul 2008],

Gene Name: KPNA6 IPOA7

Protein Name: KPNA6

Gene ID: 23633

UniProt: O60684

Pathways: Protein targeting to Nucleus