Cytokeratin 1 antibody (AA 100-200)

Catalog No. ABIN8122427

This Mouse Monoclonal antibody specifically detects Cytokeratin 1 in IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Cytokeratin 1 antibody (AA 100-200) (ABIN8122427)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1304

Product Details anti-Cytokeratin 1 Antibody

Binding Specificity: AA 100-200

Purpose: Cytokeratin mouse mAb

Specificity: The antibody can recognize multiple human Cytokeratins, including CK10, 13, 14, 15, 16, 18, 19, and it can be used for immunohistochemical detection of tumors from monolayer and multilayered epithelium.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Cytokeratin protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: Cytokeratin

Background:

Synonyms: pan cytokeRatin, wide spectrum CytokeRatin, AE1, AE3

Background: Cytokeratin can label keratinized epithelium, stratified squamous epithelium, stratified epithelium, proliferative keratinized cells and monolayer epithelium. It can be used in the study of various cancers. It is positive in various adenocarcinoma, small cell carcinoma, transitional cell carcinoma, malignant mesothelioma, germ cell tumors other than seminoma, leiomyosarcoma and some synovial sarcomas. CEA and EMA can be combined for the differential diagnosis of epithelial tumors and non epithelial tumors.

Gene Name: KRT10 KRT13 KRT14 KRT15 KRT16 KRT19

Protein Name: Cytokeratin

UniProt: P13645