KRT17 antibody (AA 300-432)

Catalog No. ABIN8122457

This Rabbit Monoclonal antibody specifically detects KRT17 in IHC. It exhibits reactivity toward Human.

Quick Overview for KRT17 antibody (AA 300-432) (ABIN8122457)

Target: KRT17 (Keratin 17 (KRT17))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KRT17 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1317

Product Details anti-KRT17 Antibody

Binding Specificity: AA 300-432

Purpose: Cytokeratin 17 (CK17) Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human CK17 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 300 - 432 of the human Cytokeratin 17 protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: Cytokeratin 17

Background:

Synonyms: 39. 1,CK 17,CK-17,CytokeRatin-17,K17,K1C17_HUMAN,KeRatin 17,keRatin 17 epitope S1,keRatin 17 epitope S2,keRatin 17 epitope S4,KeRatin 17, type I,KeRatin,KeRatin type I cytoskeletal 17,keRatin, type i cytoskeletal 17 [version 1],KeRatin-17,KRT17,PC,PC2,PCHC1,type I cytoskeletal 17

Background: CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.

Gene Name: KRT17

Protein Name: Cytokeratin 17

Gene ID: 3872

UniProt: Q04695