KRT17 antibody (AA 300-432)

Catalog No. ABIN8122459

The Mouse Monoclonal anti-KRT17 antibody (Clone AB1523) (ABIN8122459) specifically detects KRT17 in WB, IHC, IF and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for KRT17 antibody (AA 300-432) (ABIN8122459)

Target: KRT17 (Keratin 17 (KRT17))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Clone: AB1523

Product Details anti-KRT17 Antibody

Binding Specificity: AA 300-432

Purpose: Cytokeratin 17 mouse mAb

Specificity: The antibody can specifically recognize human CK17 protein. In western blotting of Hela and A431 cell lysates, the antibody can label a 46 kDa band corresponding to CK17.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 300 - 432 of the human Cytokeratin 17 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for KRT17

Target: KRT17 (Keratin 17 (KRT17))

Alternative Name: Cytokeratin 17

Background:

Synonyms: 39. 1, CK 17, CK-17, CytokeRatin-17, K17, K1C17_HUMAN, KeRatin 17, keRatin 17 epitope S1, keRatin 17 epitope S2, keRatin 17 epitope S4, KeRatin 17, type I, KeRatin, KeRatin type I cytoskeletal 17, keRatin, type i cytoskeletal 17 [version 1], KeRatin-17, KRT17, PC, PC2, PCHC1, type I cytoskeletal 17

Background: CK17 is a cytokeratin with a molecular weight of 46 kDa. It mainly marks the basal cells of stratified epithelium and pseudostratified epithelium. It is also expressed in myoepithelial cells of various glands such as breast, sweat and saliva. It is mainly used for the diagnosis of lung, cervical and oral squamous cell carcinoma. In breast cancer, the positive expression of CK17 is associated with poor prognosis, high tumor grade and axillary lymph node metastasis.

Gene Name: KRT17

Protein Name: Cytokeratin 17

Gene ID: 3872

UniProt: Q04695