Lamin B1 antibody

Catalog No. ABIN8122599

The Rabbit Monoclonal anti-Lamin B1 antibody is suitable to detect Lamin B1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, IP and IF.

Quick Overview for Lamin B1 antibody (ABIN8122599)

Target: Lamin B1 (LMNB1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AB1825

Product Details anti-Lamin B1 Antibody

Purpose: Lamin B1 Rabbit mAb

Specificity: This antibody detects endogenous levels of Lamin B1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:200-1:1000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: Lamin B1

Background:

Synonyms: LMNB1, LMN2, LMNB, Lamin-B1

Background: lamin B1 (LMNB1) Homo sapiens    This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

Gene Name: LMNB1

Protein Name: Lamin B1

Gene ID: 4001

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis