Lipin 1 antibody

Catalog No. ABIN8122666

The Rabbit Polyclonal anti-Lipin 1 antibody (ABIN8122666) specifically detects Lipin 1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Lipin 1 antibody (ABIN8122666)

Target: Lipin 1 (LPIN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lipin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Lipin 1 Antibody

Purpose: lipin1 (phospho ser889) Antibody

Specificity: This antibody detects endogenous levels of lipin1 ser889 at Human, Mouse,Rat

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human lipin1 ser889

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Lipin 1

Target: Lipin 1 (LPIN1)

Alternative Name: lipin1

Background:

Synonyms: Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Lipin-1)

Background: This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012],

Gene Name: LPIN1 KIAA0188

Protein Name: lipin1 ser889

Gene ID: 23175

UniProt: Q14693

Pathways: Monocarboxylic Acid Catabolic Process