MRPL45 antibody (AA 50-130)

Catalog No. ABIN8122967

This Rabbit Polyclonal antibody specifically detects MRPL45 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MRPL45 antibody (AA 50-130) (ABIN8122967)

Target: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL45 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MRPL45 Antibody

Binding Specificity: AA 50-130

Purpose: RM45 Antibody

Specificity: RM45 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPL45

Target: MRPL45 (Mitochondrial Ribosomal Protein L45 (MRPL45))

Alternative Name: RM45

Background:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q. [provided by RefSeq, May 2013],

Gene Name: MRPL45

Protein Name: 39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)

Gene ID: 84311

UniProt: Q9BRJ2