MRPS11 antibody (AA 10-90)

Catalog No. ABIN8122971

The Rabbit Polyclonal anti-MRPS11 antibody is suitable to detect MRPS11 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for MRPS11 antibody (AA 10-90) (ABIN8122971)

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MRPS11 Antibody

Binding Specificity: AA 10-90

Purpose: RT11 Antibody

Specificity: RT11 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS11

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Alternative Name: RT11

Background:

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Multiple transcript variants encoding different

Gene Name: MRPS11 RPMS11 HCC2

Protein Name: 28S ribosomal protein S11, mitochondrial (MRP-S11) (S11mt) (Cervical cancer proto-oncogene 2 protein) (HCC-2)

Gene ID: 64963

UniProt: P82912