MUC4 antibody (AA 2000-2100)

Catalog No. ABIN8123064

The Mouse Monoclonal anti-MUC4 antibody is suitable to detect MUC4 in samples from Human. It has been validated for IHC.

Quick Overview for MUC4 antibody (AA 2000-2100) (ABIN8123064)

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1351

Product Details anti-MUC4 Antibody

Binding Specificity: AA 2000-2100

Purpose: MUC4 mouse mAb

Specificity: The antibody can specifically recognize human MUC4 protein, and has no cross reaction wit MUC2, MUC5AC, MUC6 proteins.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 2000 - 2100 of the human MUC4 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for MUC4

Target: MUC4 (Mucin 4, Cell Surface Associated (MUC4))

Alternative Name: MUC4

Background:

Synonyms: Ascites sialoglycoprotein 1, Ascites sialoglycoprotein 2, Ascites sialoglycoprotein, ASGP, ASGP-1, ASGP-2, HSA276359, MUC 4, MUC-4, Muc4, MUC4_HUMAN, Mucin 4, Mucin 4 cell surface associated, Mucin 4 tracheobronchial, Mucin-4 beta chain, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin, Tracheobronchial mucin Fragment

Background: MUC4, also known as salivary mucin complex, exists on the surface of epithelial cells and is mainly expressed in normal tissues such as gastrointestinal tract, normal bladder epithelium, trachea, lung and testis. MUC4 is not expressed in normal pancreas, but it is expressed in most pancreatic tumors. It is also used in the study of gastric cancer, colon adenocarcinoma and lung adenocarcinoma.

Gene Name: MUC4

Protein Name: MUC4

Gene ID: 3662

UniProt: Q99102

Pathways: Regulation of Leukocyte Mediated Immunity