MUC6 antibody (AA 1000-1100)

Catalog No. ABIN8123075

This Mouse Monoclonal antibody specifically detects MUC6 in IHC. It exhibits reactivity toward Human.

Quick Overview for MUC6 antibody (AA 1000-1100) (ABIN8123075)

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC6 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1419

Product Details anti-MUC6 Antibody

Binding Specificity: AA 1000-1100

Purpose: MUC6 mouse mAb

Specificity: The antibody can specifically recognize human MUC6 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 1000 - 1100 of the human MUC6 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Alternative Name: MUC6

Background:

Synonyms: Gastric mucin 6, Gastric Mucin, Gastric mucin-6, MUC 6, MUC-6, Muc6, MUC6 Fragment, MUC6 mucin, MUC6 mucin Fragment, MUC6_HUMAN, Mucin 6, Mucin 6 gastric, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6 Fragment

Background: MUC6 is one of the secretory mucins. MUC6 is only expressed in normal gastric mucosa, also known as gastric mucus. Under physiological conditions, MUC2 is only expressed in normal intestinal mucosa (intestinal mucus) , while MUC5AC and MUC6 are only expressed in normal gastric mucosa (gastric mucus) . During tumor transformation, the expression of mucin in these tissues is changed to form a specific expression pattern. Therefore, the combination of the three has a certain significance in the differential diagnosis of gastrointestinal tumors.

Gene Name: MUC6

Protein Name: MUC6

Gene ID: 4588

UniProt: Q6W4X9