Myoferlin antibody (AA 868-918)

Catalog No. ABIN8123129

This Rabbit Polyclonal antibody specifically detects Myoferlin in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for Myoferlin antibody (AA 868-918) (ABIN8123129)

Target: Myoferlin (MYOF)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Myoferlin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Myoferlin Antibody

Binding Specificity: AA 868-918

Purpose: MYOF Antibody

Specificity: This antibody detects endogenous levels of MYOF at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human MYOF AA range: 868-918

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Myoferlin

Target: Myoferlin (MYOF)

Alternative Name: MYOF

Background:

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles.The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. [provided by RefSeq, Dec 2008],

Gene Name: MYOF FER1L3 KIAA1207

Protein Name: MYOF

Gene ID: 26509

UniProt: Q9NZM1