NAPSA antibody (AA 100-200)

Catalog No. ABIN8123240

This Mouse Monoclonal antibody specifically detects NAPSA in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for NAPSA antibody (AA 100-200) (ABIN8123240)

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NAPSA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1493

Product Details anti-NAPSA Antibody

Binding Specificity: AA 100-200

Purpose: Napsin A mouse mAb

Specificity: The antibody can specifically recognize human Napsin A protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 100 - 200 of the human Napsin A protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for NAPSA

Target: NAPSA (Napsin A Aspartic Peptidase (NAPSA))

Alternative Name: Napsin A

Background:

Synonyms: Asp 4, ASP4, Aspartyl protease 4, KAP, kDap, Kidney derived aspartic protease like protein, NAP1, NAPA, Napsa, NAPSA_HUMAN, Napsin 1, napsin A aspartic peptidase, Napsin A precursor, Napsin-1, Napsin-A, Pronapsin A, SNAPA, TA01/TA02

Background: Napsin A is a 45 kDa molecular weight gastric enzyme like aspartate protease, belonging to peptidase A1 family. The protein is highly expressed in human lung and kidney, but low in spleen. Napsin A is expressed in lung type II epithelium and lung adenocarcinoma. It has high sensitivity and specificity in lung adenocarcinoma. It is often used in combination with TTF-1 to determine whether the tumor is of lung origin.

Gene Name: NAPSA

Protein Name: Napsin A

Gene ID: 9476

UniProt: O96009

Pathways: Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis