NUMA1 antibody (pThr2055)

Catalog No. ABIN8123419

The Rabbit Polyclonal anti-NUMA1 antibody (ABIN8123419) specifically detects NUMA1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for NUMA1 antibody (pThr2055) (ABIN8123419)

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMA1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NUMA1 Antibody

Binding Specificity: pThr2055

Purpose: NuMA (Phospho Thr2055) Antibody

Specificity: This antibody detects endogenous levels of Human NuMA (phospho-Thr2055)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human NuMA (Thr2055)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for NUMA1

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Alternative Name: NuMA

Background:

Synonyms: Nuclear mitotic apparatus protein 1 (NuMA protein) (SP-H antigen)

Background: This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013],

Gene Name: NUMA1 NUMA

Protein Name: NuMA (Thr2055)

Gene ID: 4926

UniProt: Q14980

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase