OPA1 antibody

Catalog No. ABIN8123518

The Rabbit Polyclonal anti-OPA1 antibody (ABIN8123518) specifically detects OPA1 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for OPA1 antibody (ABIN8123518)

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-OPA1 Antibody

Purpose: OPA1 Antibody

Specificity: OPA1 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for OPA1

Target: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Alternative Name: OPA1

Background:

Background: This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Gene Name: OPA1 KIAA0567

Protein Name: Dynamin-like 120 kDa protein, mitochondrial (Optic atrophy protein 1) [Cleaved into: Dynamin-like 120 kDa protein, form S1]

Gene ID: 4976

UniProt: O60313

Pathways: Tube Formation