Osteocalcin antibody (AA 31-80)

Catalog No. ABIN8123530

The Rabbit Polyclonal anti-Osteocalcin antibody (ABIN8123530) specifically detects Osteocalcin in WB, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Osteocalcin antibody (AA 31-80) (ABIN8123530)

Target: Osteocalcin (BGLAP)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Osteocalcin Antibody

Binding Specificity: AA 31-80

Purpose: OSTCN Antibody

Specificity: OSTCN Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein AA range: 31-80

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: OSTCN

Background:

Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],

Gene Name: BGLAP

Protein Name: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)

Gene ID: 632

UniProt: P02818