Osteocalcin antibody

Catalog No. ABIN8123531

This Rabbit Monoclonal antibody specifically detects Osteocalcin in IHC, WB, ELISA, IP and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Osteocalcin antibody (ABIN8123531)

Target: Osteocalcin (BGLAP)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Osteocalcin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Clone: AB2210

Product Details anti-Osteocalcin Antibody

Purpose: Osteocalcin Rabbit mAb

Specificity: This antibody detects endogenous levels of Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein) protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:100-1:500 | IHC, 1:2000-1:10000 | IF, 1:200-1:1000 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for Osteocalcin

Target: Osteocalcin (BGLAP)

Alternative Name: Osteocalcin

Background:

Synonyms: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)

Background: This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1) , but the encoded protein only shows sequence identity with the upstream gene product. [provided by RefSeq, Jun 2015],

Gene Name: BGLAP

Protein Name: Osteocalcin (Bone Gla protein) (BGP) (Gamma-carboxyglutamic acid-containing protein)

Gene ID: 632

UniProt: P02818