HRPT2 antibody (AA 51-100)

Catalog No. ABIN8123592

The Rabbit Polyclonal anti-HRPT2 antibody is suitable to detect HRPT2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for HRPT2 antibody (AA 51-100) (ABIN8123592)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRPT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HRPT2 Antibody

Binding Specificity: AA 51-100

Purpose: Parafibromin Antibody

Specificity: This antibody detects endogenous levels of Parafibromin

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Parafibromin. at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Alternative Name: Parafibromin

Background:

Synonyms: Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)

Background: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],

Gene Name: CDC73 C1orf28 HRPT2

Protein Name: Parafibromin

Gene ID: 79577

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance