PDE6G antibody (pThr22)

Catalog No. ABIN8123731

The Rabbit Polyclonal anti-PDE6G antibody (ABIN8123731) specifically detects PDE6G in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PDE6G antibody (pThr22) (ABIN8123731)

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6G antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PDE6G Antibody

Binding Specificity: pThr22

Purpose: PDE6G (Phospho Thr22) Antibody

Specificity: This antibody detects endogenous levels of Human, Mouse PDE6G (Phospho Thr22)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human PDE6G (Phospho Thr22)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PDE6G

Target: PDE6G (phosphodiesterase 6G, CGMP-Specific, Rod, gamma (PDE6G))

Alternative Name: PDE6G

Background:

Synonyms: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma, EC 3.1.4.35)

Background: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],

Gene Name: PDE6G PDEG

Protein Name: PDE6G (Phospho Thr22)

Gene ID: 5148

UniProt: P18545

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction