PFKP antibody (AA 300-400)

Catalog No. ABIN8123734

The Mouse Monoclonal anti-PFKP antibody (Clone AB2400) (ABIN8123734) specifically detects PFKP in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PFKP antibody (AA 300-400) (ABIN8123734)

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This PFKP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: AB2400

Product Details anti-PFKP Antibody

Binding Specificity: AA 300-400

Purpose: PFK-C mouse mAb

Specificity: This antibody detects endogenous levels of PFK-C.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 300 - 400 of the human PFK - C protein.

Isotype: IgG

Application Details

Application Notes: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for PFKP

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Alternative Name: PFK-C

Background:

Synonyms: PFKP,PFKF,6-phosphofructokinase type C,6-phosphofructokinase,platelet type,Phosphofructo-1-kinase isozyme C,PFK-C,Phosphofructokinase 1,Phosphohexokinase

Background: This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],

Gene Name: PFKP PFKF

Protein Name: PFK-C

Gene ID: 5214

UniProt: Q01813

Pathways: Warburg Effect