PLAUR antibody

Catalog No. ABIN8123799

The Rabbit Polyclonal anti-PLAUR antibody is suitable to detect PLAUR in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for PLAUR antibody (ABIN8123799)

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAUR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLAUR Antibody

Purpose: U-PAR Antibody

Specificity: This antibody detects endogenous levels of Human U-PAR

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human U-PAR

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PLAUR

Target: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Alternative Name: U-PAR

Background:

Synonyms: Urokinase plasminogen activator surface receptor (U-PAR, uPAR, Monocyte activation antigen Mo3, CD antigen CD87)

Background: function:Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.,similarity:Contains 3 UPAR/Ly6 domains.,subunit:Monomer (Probable). Interacts with MRC2.,

Gene Name: PLAUR MO3 UPAR

Protein Name: U-PAR

Gene ID: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process