POU2AF1 antibody (AA 150-256)

Catalog No. ABIN8123904

The Rabbit Monoclonal anti-POU2AF1 antibody is suitable to detect POU2AF1 in samples from Human and Mouse. It has been validated for IHC.

Quick Overview for POU2AF1 antibody (AA 150-256) (ABIN8123904)

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This POU2AF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1268

Product Details anti-POU2AF1 Antibody

Binding Specificity: AA 150-256

Purpose: BOB.1 Rabbit mAb (Ready to Use)

Specificity: The antibody can specifically recognize human BOB. 1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 150 - 256 of the human BOB. 1 protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for POU2AF1

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Alternative Name: BOB.1

Background:

Synonyms: B cell Oct binding protein 1,B cell specific coactivator OBF 1,B cell specific coactivator OBF1,B-cell-specific coactivator OBF-1,BOB 1,BOB-1,OBF 1,OBF1,OBF1_HUMAN,OCA B,OCA-B,OCAB,OCT binding factor 1,OCT-binding factor 1,POU class 2 associating factor 1,POU domain class 2 associating factor 1,POU domain class 2-associating factor 1,Pou2af1

Background: BOB. 1 is a transcription activating factor necessary for the formation of follicular germinal center and the production of immunoglobulin. It works together with Oct- 2 and is highly expressed in granulocytes of spleen and peripheral blood. It is mainly used for the typing of Hodgkin's lymphoma, mainly nodular lymphocytes. Hodgkin's lymphoma is positive and classical Hodgkin's lymphoma is negative.

Gene Name: POU2AF1

Protein Name: BOB. 1

Gene ID: 5450

UniProt: Q16633