RASGRP3 antibody (AA 90-170)

Catalog No. ABIN8124241

The Rabbit Polyclonal anti-RASGRP3 antibody (ABIN8124241) specifically detects RASGRP3 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RASGRP3 antibody (AA 90-170) (ABIN8124241)

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RASGRP3 Antibody

Binding Specificity: AA 90-170

Purpose: GRP3 Antibody

Specificity: GRP3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RASGRP3

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Alternative Name: GRP3

Background:

Background: RAS guanyl releasing protein 3(RASGRP3) Homo sapiens Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008],

Gene Name: RASGRP3 GRP3 KIAA0846

Protein Name: Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)

Gene ID: 25780

UniProt: Q8IV61