Reelin antibody (AA 270-350)

Catalog No. ABIN8124300

The Rabbit Polyclonal anti-Reelin antibody is suitable to detect Reelin in samples from Human and Rat. It has been validated for IHC and IF.

Quick Overview for Reelin antibody (AA 270-350) (ABIN8124300)

Target: Reelin (RELN)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Reelin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Reelin Antibody

Binding Specificity: AA 270-350

Purpose: RELN Antibody

Specificity: RELN Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: IHC 1:50-300. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Reelin

Target: Reelin (RELN)

Alternative Name: RELN

Background:

Background: This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: RELN

Protein Name: Reelin (EC 3.4.21.-)

Gene ID: 5649

UniProt: P78509

Pathways: Synaptic Membrane