RIMS2 antibody (AA 200-300)

Catalog No. ABIN8124303

The Mouse Monoclonal anti-RIMS2 antibody is suitable to detect RIMS2 in samples from Human. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for RIMS2 antibody (AA 200-300) (ABIN8124303)

Target: RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RIMS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: AB2414

Product Details anti-RIMS2 Antibody

Binding Specificity: AA 200-300

Purpose: Nuclear protein mouse mAb

Specificity: This antibody detects endogenous levels of Nuclear protein (NeuN) protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 200 - 300 of the human Nuclear protein protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for RIMS2

Target: RIMS2 (Regulating Synaptic Membrane Exocytosis 2 (RIMS2))

Alternative Name: Nuclear protein

Background:

Synonyms: RNA binding protein fox-1 homolog 3,Fox-1 homolog C,

Background: This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017]

Gene Name: RBFOX3

Protein Name: Nuclear protein

Gene ID: 146713

UniProt: A6NFN3

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis