Rhotekin antibody (AA 80-160)

Catalog No. ABIN8124370

The Rabbit Polyclonal anti-Rhotekin antibody (ABIN8124370) specifically detects Rhotekin in IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Rhotekin antibody (AA 80-160) (ABIN8124370)

Target: Rhotekin (RTKN)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rhotekin antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Rhotekin Antibody

Binding Specificity: AA 80-160

Purpose: Rhotekin Antibody

Specificity: Rhotekin Polyclonal Antibody detects endogenous levels of Rhotekin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from Rhotekin . at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Rhotekin

Target: Rhotekin (RTKN)

Alternative Name: Rhotekin

Background:

Synonyms: RTKN, RTKN1, Rhotekin

Background: This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: RTKN

Protein Name: Rhotekin

Gene ID: 6242

UniProt: Q9BST9