RPLP2 antibody (AA 170-250)

Catalog No. ABIN8124428

This Rabbit Polyclonal antibody specifically detects RPLP2 in ELISA and WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for RPLP2 antibody (AA 170-250) (ABIN8124428)

Target: RPLP2 (Ribosomal Protein, Large, P2 (RPLP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPLP2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-RPLP2 Antibody

Binding Specificity: AA 170-250

Purpose: AntibodyP2 Antibody

Specificity: PABP2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 170-250

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RPLP2

Target: RPLP2 (Ribosomal Protein, Large, P2 (RPLP2))

Alternative Name: P2

Background:

Background: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010],

Gene Name: PABPN1 PAB2 PABP2

Protein Name: Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)

Gene ID: 8106

UniProt: Q86U42