RNF4 antibody (AA 71-121)

Catalog No. ABIN8124444

The Rabbit Polyclonal anti-RNF4 antibody is suitable to detect RNF4 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IHC.

Quick Overview for RNF4 antibody (AA 71-121) (ABIN8124444)

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RNF4 Antibody

Binding Specificity: AA 71-121

Purpose: RNF4 Antibody

Specificity: This antibody detects endogenous levels of RNF4 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human RNF4 AA range: 71-121

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for RNF4

Target: RNF4 (Ring Finger Protein 4 (RNF4))

Alternative Name: RNF4

Background:

Background: The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010],

Gene Name: RNF4 SNURF RES4-26

Protein Name: RNF4

Gene ID: 6047

UniProt: P78317

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway