Ryncolin-1-Like antibody

Catalog No. ABIN8124495

The Rabbit Polyclonal anti-Ryncolin-1-Like antibody is suitable to detect Ryncolin-1-Like in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IF and IHC.

Quick Overview for Ryncolin-1-Like antibody (ABIN8124495)

Target: Ryncolin-1-Like (LOC108969966)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ryncolin-1-Like antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-Ryncolin-1-Like Antibody

Purpose: TNR8 Antibody

Specificity: TNR8 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 IHC: 50-200 ELISA 1:5000-20000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Ryncolin-1-Like

Target: Ryncolin-1-Like (LOC108969966)

Alternative Name: TNR8

Background:

Background: The protein encoded byThis gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

Gene Name: TNFRSF8 CD30 D1S166E

Protein Name: Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)

Gene ID: 943

UniProt: P28908