SRPK2 antibody

Catalog No. ABIN8124649

The Rabbit Polyclonal anti-SRPK2 antibody (ABIN8124649) specifically detects SRPK2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for SRPK2 antibody (ABIN8124649)

Target: SRPK2 (SFRS Protein Kinase 2 (SRPK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRPK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SRPK2 Antibody

Purpose: SRPK2 Antibody

Specificity: SRPK2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SRPK2

Target: SRPK2 (SFRS Protein Kinase 2 (SRPK2))

Alternative Name: SRPK2

Background:

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Ser-52 and Ser-588.,function:Phosphorylates RS domain-containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.,sequence caution:The cDNA appears to contain a duplicated region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in brain, moderately expressed in heart and skeletal muscle and at low levels in lung, liver, and kidney.,

Gene Name: SRPK2

Protein Name: SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminalSRSF protein kinase 2 C-terminal]

Gene ID: 6733

UniProt: P78362

Pathways: Ribonucleoprotein Complex Subunit Organization