SHOX2 antibody (AA 37-87)

Catalog No. ABIN8124660

The Rabbit Polyclonal anti-SHOX2 antibody is suitable to detect SHOX2 in samples from Human, Rat and Mouse. It has been validated for WB, IHC and FACS.

Quick Overview for SHOX2 antibody (AA 37-87) (ABIN8124660)

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHOX2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-SHOX2 Antibody

Binding Specificity: AA 37-87

Purpose: SHOX2 Antibody

Specificity: This antibody detects endogenous levels of SHOX2 at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SHOX2 AA range: 37-87

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300,FCM 1:100-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SHOX2

Target: SHOX2 (Short Stature Homeobox 2 (SHOX2))

Alternative Name: SHOX2

Background:

Background: This gene is a member of the homeobox family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeobox genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeobox genes. This locus represents a pseudoautosomal homeobox gene that is thought to be responsible for idiopathic short stature, and it is implicated in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],

Gene Name: SHOX2 OG12X SHOT

Protein Name: SHOX2

Gene ID: 6474

UniProt: O60902

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development