SAP18 antibody

Catalog No. ABIN8124708

The Rabbit Polyclonal anti-SAP18 antibody is suitable to detect SAP18 in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for SAP18 antibody (ABIN8124708)

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SAP18 Antibody

Purpose: SAP18 Antibody

Specificity: This antibody detects endogenous levels of SAP18 at Human/Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human SAP18

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SAP18

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: SAP18

Background:

Background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes.The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008],

Gene Name: SAP18 GIG38

Protein Name: SAP18

Gene ID: 10284

UniProt: O00422