SLAMF7 antibody (AA 41-90)

Catalog No. ABIN8124723

The Rabbit Polyclonal anti-SLAMF7 antibody is suitable to detect SLAMF7 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for SLAMF7 antibody (AA 41-90) (ABIN8124723)

Target: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLAMF7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLAMF7 Antibody

Binding Specificity: AA 41-90

Purpose: SLAF7 Antibody

Specificity: SLAF7 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein AA range: 41-90

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SLAMF7

Target: SLAMF7 (SLAM Family Member 7 (SLAMF7))

Alternative Name: SLAF7

Background:

Background: function:Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro).,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,tissue specificity:Expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level tha isoform 1.,

Gene Name: SLAMF7 CS1 UNQ576/PRO1138

Protein Name: SLAM family member 7 (CD2 subset 1) (CD2-like receptor-activating cytotoxic cells) (CRACC) (Membrane protein FOAP-12) (Novel Ly9) (Protein 19A) (CD antigen CD319)

Gene ID: 57823

UniProt: Q9NQ25