SLC25A27 antibody (AA 110-190)

Catalog No. ABIN8124813

The Rabbit Polyclonal anti-SLC25A27 antibody is suitable to detect SLC25A27 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SLC25A27 antibody (AA 110-190) (ABIN8124813)

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A27 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC25A27 Antibody

Binding Specificity: AA 110-190

Purpose: UCP4 Antibody

Specificity: UCP4 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SLC25A27

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Alternative Name: UCP4

Background:

Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.[provided by RefSeq,

Gene Name: SLC25A27 UCP4 UNQ772/PRO1566

Protein Name: Mitochondrial uncoupling protein 4 (UCP 4) (Solute carrier family 25 member 27)

Gene ID: 9481

UniProt: O95847