Sortilin 1 antibody (AA 260-340)

Catalog No. ABIN8124855

The Rabbit Polyclonal anti-Sortilin 1 antibody is suitable to detect Sortilin 1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for Sortilin 1 antibody (AA 260-340) (ABIN8124855)

Target: Sortilin 1 (SORT1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sortilin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Sortilin 1 Antibody

Binding Specificity: AA 260-340

Purpose: SORT Antibody

Specificity: SORT Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Sortilin 1

Target: Sortilin 1 (SORT1)

Alternative Name: SORT

Background:

Background: This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Gene Name: SORT1

Protein Name: Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)

Gene ID: 6272

UniProt: Q99523

Pathways: Neurotrophin Signaling Pathway