SPA17 antibody (AA 23-73)

Catalog No. ABIN8124883

The Rabbit Polyclonal anti-SPA17 antibody (ABIN8124883) specifically detects SPA17 in IHC and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for SPA17 antibody (AA 23-73) (ABIN8124883)

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPA17 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SPA17 Antibody

Binding Specificity: AA 23-73

Purpose: NEUG Antibody

Specificity: This antibody detects endogenous levels of NEUG at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NEUG AA range: 23-73

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Alternative Name: NEUG

Background:

Background: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene.This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008],

Gene Name: NRGN

Protein Name: NEUG

Gene ID: 4900

UniProt: Q92686