Stabilin 2 (STAB2) (AA 980-1060) antibody

Catalog No. ABIN8124941

This Rabbit Polyclonal antibody specifically detects Stabilin 2 in IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Stabilin 2 (STAB2) (AA 980-1060) antibody (ABIN8124941)

Target: Stabilin 2 (STAB2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 980-1060

Purpose: STAB2 Antibody

Specificity: STAB2 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 980-1060

Isotype: IgG

Application Details

Application Notes: IHC 1:50-300 IF 1:100-300 Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details

Target: Stabilin 2 (STAB2)

Alternative Name: STAB2

Background:

Background: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008],

Gene Name: STAB2 FEEL2 FELL FEX2 HARE

Protein Name: Stabilin-2 (FAS1 EGF-like and X-link domain-containing adhesion molecule 2) (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2) (FEEL-2) (Hyaluronan receptor for endocytosis) [Cleaved into: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)]

Gene ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process