STARD4 antibody

Catalog No. ABIN8124947

This Rabbit Monoclonal antibody specifically detects STARD4 in WB, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for STARD4 antibody (ABIN8124947)

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This STARD4 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: AB2258

Product Details anti-STARD4 Antibody

Purpose: STARD4 Rabbit mAb

Specificity: This antibody detects endogenous levels of STARD4 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IF, 1:100-1:300 |

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for STARD4

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Alternative Name: STARD4

Background:

Synonyms: STARD4, StAR-related lipid transfer protein 4 , START domain-containing protein 4, StARD4,

Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e. g. , SREBP1, MIM 184756) and by liver X receptors (e. g. , LXRA, MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617) . STAR is homologous to a family of proteins containing a 200-to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al. , 2002 [PubMed 12011452]) . [supplied by OMIM, Mar 2008]

Gene Name: STARD4

Protein Name: STARD4

Gene ID: 134429

UniProt: Q96DR4